Core equimpent of the MCPI department
Laboratory facilities
We are a LEAF-Silver certified sustainable synthetic laboratory located at the UMCG Healthy Ageing Campus in Groningen, in the direct vicinity of the hospital, animal facility, proton therapy center and nuclear medicine department. Our premises feature 27 fumehoods and an array of synthetic and analytical equipment outlined below, including a dedicated dark room.
Synthesis and Purification
Microwave oven
Biotage Initiator+.
Lyophilizer
Buchi Lyovapor 200.
Autocolumn Grace x2 and GracePURE
Semi-preparative HPLC
Shimadzu HPLC system.
Preparative HPLC
Shimadzu HPLC system.
Compound Characterisation
NMR 400 MHz
JNM-ECZL400S 400 MHz 9.4 T NMR Spectrometer equipped with a 5mm Royal Probe HFX.
UPLC-MS
Agilent 1290 Infinity II UHPLC (1300 bar) with Diode Array Detector and LC/MSD iQ Mass Selective Detector.
TLC-MS
Advion expression.
NMRD Relaxometer
Stelar 0.25 T FFC relaxometer SMARtracer.
Photochemistry
UV-Vis spectrophotometer with in situ irradiation setup
Agilent Cary 60 spectrophotometer with a custom-built (Prizmatix) multi-wavelength fiber coupled LED-system (FC10-LED-USB) connected through a fiber bundle attached to a liquid light guide.
Spectrofluorimeter
Edinburgh Instruments FS5 spectrofluorometer equipped with the SC-20 Thermostatic Sample Holder and integrating sphere (SC-30).
Plate Reader
BioTek Synergy H1M plate reader with an extended PMT range for fluorescence measurements (up to 900 nm).